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Review
. 1998 Jan;23(1):10-4.
doi: 10.1016/s0968-0004(97)01143-2.

The endoplasmic reticulum Ca2+ store: a view from the lumen

J Meldolesi  1 , T Pozzan
Affiliations
Review

The endoplasmic reticulum Ca2+ store: a view from the lumen

J Meldolesi et al. Trends Biochem Sci. 1998 Jan.

Abstract

The endoplasmic reticulum (ER) and its specialized subcompartments such as the sarcoplasmic reticulum, is the main dynamic Ca2+ storage compartment of the cell. Key cellular functions are regulated, either directly or indirectly, by the free Ca2+ concentration in the ER. This article discusses the properties of Ca2+ storage in the ER and considers the functions that appear to be regulated by the Ca2+ stores within the ER, both in and around the ER and at a distance from it.

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