Isolation of (copper, zinc-) thioneins from pig liver
- PMID: 949324
- PMCID: PMC1172886
- DOI: 10.1042/bj1550631
Isolation of (copper, zinc-) thioneins from pig liver
Abstract
The copper-binding proteins with mol. wt. of approx. 12000 in the cytosol of pig liver have been identified as copper-thioneins. They contain variable amounts of zinc, with approx. 10% total metal in the protein. The molar cysteine/metal ratio is approx. 2:1.
Similar articles
-
Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats.Biochem J. 1976 Aug 1;157(2):517-20. doi: 10.1042/bj1570517. Biochem J. 1976. PMID: 962883 Free PMC article.
-
Metal-binding proteins in bovine and porcine hepatic and renal tissues: isolation and characterization.Am J Vet Res. 1980 Apr;41(4):548-51. Am J Vet Res. 1980. PMID: 7406274
-
Purification and characterization of zinc-binding protein from the liver of the partially hepatectomized rat.Biochem J. 1979 Dec 1;183(3):683-90. doi: 10.1042/bj1830683. Biochem J. 1979. PMID: 540039 Free PMC article.
-
Hepatic copper- and zinc-binding proteins in ruminants. 2. Relationship between Cu and Zn concentrations and the occurrence of a metallothionein-like fraction.Br J Nutr. 1974 Sep;32(2):293-300. doi: 10.1079/bjn19740082. Br J Nutr. 1974. PMID: 4424627 No abstract available.
-
Purification and properties of plaice metallothionein, a cadmium-binding protein from the liver of the plaice (Pleuronectes platessa).Biochem J. 1979 Nov 1;183(2):277-83. doi: 10.1042/bj1830277. Biochem J. 1979. PMID: 534496 Free PMC article.
Cited by
-
Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals.Biochem J. 1984 Apr 15;219(2):539-46. doi: 10.1042/bj2190539. Biochem J. 1984. PMID: 6743231 Free PMC article.
-
Copper-metallothioneins in the American lobster, Homarus americanus: potential role as Cu(I) donors to apohemocyanin.Environ Health Perspect. 1986 Mar;65:93-100. doi: 10.1289/ehp.866593. Environ Health Perspect. 1986. PMID: 3709470 Free PMC article.
-
Effect of zinc status of rats on the synthesis and degradation of copper-induced metallothioneins.Biochem J. 1978 Sep 15;174(3):883-92. doi: 10.1042/bj1740883. Biochem J. 1978. PMID: 728094 Free PMC article.
-
On the sensitivity of metallothioneins to oxidation during isolation.Biochem J. 1980 Nov 1;191(2):475-85. doi: 10.1042/bj1910475. Biochem J. 1980. PMID: 7236206 Free PMC article.
-
Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats.Biochem J. 1976 Aug 1;157(2):517-20. doi: 10.1042/bj1570517. Biochem J. 1976. PMID: 962883 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources