[Antigenic markers of variable region of mouse myeloma MOPC 21 light chain]
[Article in
Russian]
- PMID: 94936
Item in Clipboard
[Antigenic markers of variable region of mouse myeloma MOPC 21 light chain]
[Article in
Russian]
Mol Biol (Mosk).
1979 Nov-Dec.
Abstract
Monospecific antibodies against V-region of the L-chain of the mouse myeloma protein MOPC21 (VK 15 group) were obtained and used for preparation of antibody-immunoadsorbents. By means of the immunoadsorbents the content of normal immunoglobulins with antigenic markers of VK 15 group in the serum of mouse strains BALB/c, CBA and C57BL/6 was determined. The least quantity of the proteins determined by this method was estimated to be 1.4%. If each of K-chains of the variable groups is represented equally in the population of normal immunoglobulins, the number of VK groups and respectively germ-line VK genes should be not less than 70.
Similar articles
-
Antigenic markers of V domain of mouse MOPC 21 IgG1 L chain. The conformational basis of VL domain markers and content of MOPC 21 VL-like immunoglobulins in sera of inbred mouse strains.Eur J Immunol. 1983 May;13(5):397-403. doi: 10.1002/eji.1830130509. Eur J Immunol. 1983. PMID: 6189726
-
[Immunochemical study of the conformational properties of the variable and constant domains of the light chain of mouse MOPC myeloma immunoglobulin].Mol Biol (Mosk). 1980 Sep-Oct;14(5):1187-92. Mol Biol (Mosk). 1980. PMID: 6158677 Russian.
-
Amino acid sequence of a phosphocholine-binding antibody from an immune defective CBA/N mouse employing the T15 VH region associated with unusual DH, JH, and V kappa segments.J Immunol. 1984 Mar;132(3):1544-9. J Immunol. 1984. PMID: 6420465
-
Structural and functional mapping of immunoglobulin V-regions.Ann Immunol (Paris). 1976 Jun-Jul;127(3-4):285-302. Ann Immunol (Paris). 1976. PMID: 60901 Review.
-
Significance of paraproteins in neoplastic disease.Prog Exp Tumor Res. 1974;19:59-90. doi: 10.1159/000395849. Prog Exp Tumor Res. 1974. PMID: 4216042 Review. No abstract available.