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. 1979 Nov-Dec;13(6):1303-11.

[Antigenic markers of variable region of mouse myeloma MOPC 21 light chain]

[Article in Russian]
T I Vengerova, M N Petrosian, G T Bogacheva, O V Rokhlin
  • PMID: 94936

[Antigenic markers of variable region of mouse myeloma MOPC 21 light chain]

[Article in Russian]
T I Vengerova et al. Mol Biol (Mosk). 1979 Nov-Dec.

Abstract

Monospecific antibodies against V-region of the L-chain of the mouse myeloma protein MOPC21 (VK 15 group) were obtained and used for preparation of antibody-immunoadsorbents. By means of the immunoadsorbents the content of normal immunoglobulins with antigenic markers of VK 15 group in the serum of mouse strains BALB/c, CBA and C57BL/6 was determined. The least quantity of the proteins determined by this method was estimated to be 1.4%. If each of K-chains of the variable groups is represented equally in the population of normal immunoglobulins, the number of VK groups and respectively germ-line VK genes should be not less than 70.

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