Quinolinic acid: effect on the nucleus arcuatus of the hypothalamus in the rat (ultrastructural evidence)
- PMID: 9495649
- DOI: 10.1016/S0940-2993(97)80141-8
Quinolinic acid: effect on the nucleus arcuatus of the hypothalamus in the rat (ultrastructural evidence)
Abstract
Quinolinic acid was administered intraperitoneally to male Wistar rats in a dose of 60 mmol, once daily for 8 days. By electron microscopy, in quinolinic acid-treated rats, the neuronal cell bodies in the arcuate nucleus had features of increased cellular activity, but some damage of neuronal cell bodies was also evident.
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