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Review
. 1998;3(1):R9-23.
doi: 10.1016/S1359-0278(98)00002-9.

Protein aggregation: folding aggregates, inclusion bodies and amyloid

A L Fink  1
Affiliations
Review

Protein aggregation: folding aggregates, inclusion bodies and amyloid

A L Fink. Fold Des. 1998.

Abstract

Aggregation results in the formation of inclusion bodies, amyloid fibrils and folding aggregates. Substantial data support the hypothesis that partially folded intermediates are key precursors to aggregates, that aggregation involves specific intermolecular interactions and that most aggregates involve beta sheets.

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