Review
doi: 10.1016/S1359-0278(98)00002-9.
Protein aggregation: folding aggregates, inclusion bodies and amyloid
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- PMID: 9502314
- DOI: 10.1016/S1359-0278(98)00002-9
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Review
Protein aggregation: folding aggregates, inclusion bodies and amyloid
Fold Des.
1998.
Abstract
Aggregation results in the formation of inclusion bodies, amyloid fibrils and folding aggregates. Substantial data support the hypothesis that partially folded intermediates are key precursors to aggregates, that aggregation involves specific intermolecular interactions and that most aggregates involve beta sheets.
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