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. 1976 Jun;29(6):653-5.
doi: 10.7164/antibiotics.29.653.

CGP 9000: a new orally active, broad-spectrum cephalosporin

O Zak, W A Vischer, C Schenk, W Tosch, W Zimmermann, J Regös, E R Suter, F Kradolfer, J Gelzer
Free article

CGP 9000: a new orally active, broad-spectrum cephalosporin

O Zak et al. J Antibiot (Tokyo). 1976 Jun.
Free article

Abstract

CGP 9000, (7-[D-2-amino-2-(1,4-cyclohexadienyl)-acetamido]-3-methoxy-3-cephem-4-carboxylic acid), is a new broad-spectrum cephalosporin antibiotic. Its antibacterial activity in vitro (MIC) is similar, but its bactericidal efficacy superior to that of cephalexin and cephradine. Upon oral administration to mice infected with various bacteria, CGP 9000 is, in general, 2 to 7 times more effective than either cephalexin or cephradine.

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