Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1998 Feb;35(2):151-2.
doi: 10.1136/jmg.35.2.151.

A Moroccan family with autosomal recessive sensorineural hearing loss caused by a mutation in the gap junction protein gene connexin 26 (GJB2)

N J Lench  1 , A F Markham, R F Mueller, D P Kelsell, R J Smith, P J Willems, I Schatteman, H Capon, P J Van De Heyning, G Van Camp
Affiliations
Case Reports

A Moroccan family with autosomal recessive sensorineural hearing loss caused by a mutation in the gap junction protein gene connexin 26 (GJB2)

N J Lench et al. J Med Genet. 1998 Feb.

Abstract

We report a mutation in the connexin 26 gene (Cx26) in a consanguineous Moroccan family linked to the DFNA3/DFNB1 locus on human chromosome 13q11-q12. Affected subjects display congenital, bilateral, sensorineural hearing loss. We have previously identified Cx26 mutations in consanguineous Pakistani families. This current finding indicates that Cx26 mutations are not restricted to ethnically and geographically distinct populations. This is an important observation since it will help to determine the overall contribution of connexin 26 mutations to autosomal deafness in different populations.

PubMed Disclaimer

References

    1. Am J Hum Genet. 1995 Sep;57(3):629-35 - PubMed
    1. Nature. 1997 May 1;387(6628):80-3 - PubMed
    1. Am J Hum Genet. 1997 Apr;60(4):758-64 - PubMed
    1. Cell. 1996 Feb 9;84(3):381-8 - PubMed

Publication types

MeSH terms

LinkOut - more resources