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Review
. 1997 Jul-Aug;45(4):371-6; quiz 379-80.

Medication-induced gingival enlargement: a clinical review

L H Silverstein  1 , J J Garnick, M Szikman, B Singh
Affiliations
  • PMID: 9515445
Review

Medication-induced gingival enlargement: a clinical review

L H Silverstein et al. Gen Dent. 1997 Jul-Aug.

Abstract

This review discusses the etiology and treatment of gingival hyperplasia. It cites evidence that medications such as phenytoin, an anticonvulsant; cyclosporine, an immunosuppressant; and numerous calcium channel blocking agents have been shown clinically and histologically to produce analogous gingival enlargements. A multiphasic approach to treating disfiguring gingival hyperplasia through mechanical and chemical plaque control, in conjunction with the surgical removal of the hyperplastic tissue, is discussed.

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