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Comparative Study
. 1976:22:654-63.

Successful use of a totally heparin grafted hemodialysis system in sheep

G Schmer, L N Teng, J J Cole, J E Vizzo, M M Francisco, B H Scribner
  • PMID: 951885
Comparative Study

Successful use of a totally heparin grafted hemodialysis system in sheep

G Schmer et al. Trans Am Soc Artif Intern Organs. 1976.

Abstract

A total of 33 totally heparin-grafted dialysis systems using HFAK Cordis Dow Models 3 and 4 have been compared to a total of 23 nongrafted systems. The comparison of deltap, flow rate, FBVL and macroscopic inspection showed highly significant differences in favor of the heparin-grafted systems. The antithrombogenic performance of the totally heparin-grafted systems is mainly due to a small leakage of heparin during the experiments. A minimum of 1.35 X 10(-8) Gm/cm2/min of heparin is sufficient to prevent clotting at the blood-polymer interface.

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