Review
doi: 10.1016/s0959-440x(98)80006-7.
Type II DNA topoisomerases
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- PMID: 9519293
- DOI: 10.1016/s0959-440x(98)80006-7
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Review
Type II DNA topoisomerases
Curr Opin Struct Biol.
1998 Feb.
Abstract
Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.
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