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Review
. 1998 Feb;8(1):26-32.
doi: 10.1016/s0959-440x(98)80006-7.

Type II DNA topoisomerases

J M Berger  1
Affiliations
Review

Type II DNA topoisomerases

J M Berger. Curr Opin Struct Biol. 1998 Feb.

Abstract

Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.

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