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. 1998 Mar 31;95(7):3341-3.
doi: 10.1073/pnas.95.7.3341.

To muster a cluster: anchoring neurotransmitter receptors at synapses

M Colledge  1 , S C Froehner
Affiliations

To muster a cluster: anchoring neurotransmitter receptors at synapses

M Colledge et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Structural domains of rapsyn. The N-terminal myristoylation site (Myr) targets rapsyn to the plasma membrane. The first two TPR domains are sufficient to mediate rapsyn self-clustering. Whether other TPR domains also can serve this function remains to be determined. The ability of rapsyn to promote AChR clustering appears to depend on a putative coiled-coil motif. TPR domains not involved in rapsyn self-association as well as the zinc ring finger (RING) domain are likely to be sites of interaction with other postsynaptic proteins. The function of the phosphorylation site (P) is unknown.
See this image and copyright information in PMC

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