doi: 10.1038/282582a0.
Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells
- PMID: 95208
- DOI: 10.1038/282582a0
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Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells
Nature.
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Abstract
Until now the interferon-mediated 2'-5' adenine oligonucleotide inhibitors (2-5A) of cell-free protein synthesis have not been detected in intact cells. Here we report their natural occurrence in interferon-treated, EMC virus-infected mouse L cells in amounts consistent with the idea that they play a part in the inhibition of virus growth.
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