Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1998 Mar 1;48(2):258-64.
doi: 10.1006/geno.1997.5171.

Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene

I M Bennani-Baïti  1 , N E Cooke, S A Liebhaber
Affiliations
Free article

Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene

I M Bennani-Baïti et al. Genomics. .
Free article

Abstract

We have previously characterized a locus control region for the GH1 gene consisting of four DNase I hypersensitive sites (HS) located between 14.5 and 32 kb 5' to the GH1 gene transcription start site. Sequence analysis of the region between the GH1 gene and its most proximal HS (HSI) revealed a perfect match to the B-lymphocyte-specific CD79b gene. Restriction mapping and hybridization analysis of YAC and cosmid clones confirmed the close linkage of the CD79b gene to the hGH gene cluster and facilitated the assembly of a 100-kb physical map linking the hGH locus, the CD79b gene, and the more distant muscle-specific sodium channel alpha-subunit (SCN4A) gene.

PubMed Disclaimer

Publication types

Associated data

LinkOut - more resources