The use of sedation and muscle relaxation in the ventilated infant

Abstract

The use of sedation, muscle relaxation, or analgesia in the management of ventilated neonates has been controversial. Many neonatologists face a difficult decision on whether or not to use a muscle relaxant on a ventilated infant. This article reviews neonatal physiology and pharmacology, drug administration, absorption, distribution, and certain selected sedatives and analgesics. The muscle relaxants, financial issues, and family issues are also discussed.