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Review
. 1998 Feb;10(1):12-5.
doi: 10.1016/s0952-7915(98)80024-1.

An ancient system of host defense

R Medzhitov  1 , C A Janeway Jr
Affiliations
Free article
Review

An ancient system of host defense

R Medzhitov et al. Curr Opin Immunol. 1998 Feb.
Free article

Abstract

Research over the past few years has begun to provide significant advances in our understanding of the interplay between the innate and adaptive immune systems. New findings in several model systems reveal remarkable parallels and conservation of ancient host defense pathways in organisms separated by over a billion years of evolution.

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