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. 1995 Jan-Jun;99(1-2):124-8.

[The isolation and subtyping of the human immunodeficiency virus (HIV) from children in Moldova. The evidence for subtype F]

[Article in Romanian]
C Apetrei  1 , G Collin, D Diculencu, I L Ajaka, I Farfara, C Pânzaru, G Coman, M Duca, F Brun-Vezinet, F Simon
Affiliations
  • PMID: 9524668

[The isolation and subtyping of the human immunodeficiency virus (HIV) from children in Moldova. The evidence for subtype F]

[Article in Romanian]
C Apetrei et al. Rev Med Chir Soc Med Nat Iasi. 1995 Jan-Jun.

Abstract

HIV epidemic related to nosocomial transmission in Romanian nursed children represents up to now more than 50% of paediatric AIDS cases in Europe. Although the sources of this epidemic are obscure, HIV-1 subtype F, a minor form in Brasil and Africa, realised a founder effect in this risk group, thus becoming the major form in Romanian epidemic. This study presents the results of the virus isolation from HIV-infected children in Northeast Romania. Heteroduplex mobility assay (HMA) was performed in order to establish HIV-1 viral subtype for 6 isolates. All tested HIV-1 strains were proved to belong to F subtype. So, our study confirm that HIV-1 subtype F is responsible for the epidemic in the risk group of Romanian nosocomially infected children.

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