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Review
. 1998 Mar;65(3):868-74.
doi: 10.1016/s0003-4975(97)01377-5.

The biology of estrogen-mediated repair of cardiovascular injury

C H Selzman  1 , T A Whitehill, B D Shames, E J Pulido, B S Cain, A H Harken
Affiliations
Review

The biology of estrogen-mediated repair of cardiovascular injury

C H Selzman et al. Ann Thorac Surg. 1998 Mar.

Erratum in

  • Ann Thorac Surg 1998 Jul;66(1):310. Cain BC [corrected to Cain BS]

Abstract

Women appear to be protected from cardiovascular disease until the onset of menopause. Considerable evidence supports the atheroprotective effects of endogenous and supplemental estrogens. The beneficial effects of estrogens on lipid metabolism cannot wholly explain this phenomenon. Accumulating data suggest that estrogen may act at the cellular and molecular level to influence atherogenesis. The purpose of this review is to examine lipid-independent mechanisms of estrogen-mediated atheroprotection after cardiovascular injury.

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