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Review
. 1998 Feb;8(1):82-7.
doi: 10.1016/s0959-437x(98)80066-x.

The fight of viruses against apoptosis

J Tschopp  1 , M Thome, K Hofmann, E Meinl
Affiliations
Review

The fight of viruses against apoptosis

J Tschopp et al. Curr Opin Genet Dev. 1998 Feb.

Abstract

The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.

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