Ineffectiveness of oral coenzyme Q10 supplementation in 3-methylglutaconic aciduria, type 3
- PMID: 9533558
- DOI: 10.1016/s0387-7604(97)00096-x
Ineffectiveness of oral coenzyme Q10 supplementation in 3-methylglutaconic aciduria, type 3
Abstract
Coenzyme Q10 was administered under placebo controlled blinded crossover conditions to six subjects suffering from type 3 3-methylglutaconic aciduria ('optic atrophy plus'), following a report of benefit. Despite attainment of high plasma levels of coenzyme Q10, no clinical benefit was observed and there was no diminution of urinary excretion of 3-methylglutaconic acid.
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