Comment on

• Primary afferent tachykinins are required to experience moderate to intense pain.

  Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Cao YQ, et al. Nature. 1998 Mar 26;392(6674):390-4. doi: 10.1038/32897. Nature. 1998. PMID: 9537322
• Altered nociception, analgesia and aggression in mice lacking the receptor for substance P.

  De Felipe C, Herrero JF, O'Brien JA, Palmer JA, Doyle CA, Smith AJ, Laird JM, Belmonte C, Cervero F, Hunt SP. De Felipe C, et al. Nature. 1998 Mar 26;392(6674):394-7. doi: 10.1038/32904. Nature. 1998. PMID: 9537323