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Review
. 1998 Apr 14;95(8):4084-5.
doi: 10.1073/pnas.95.8.4084.

Stability without a centromere

M P Calos  1
Affiliations
Review

Stability without a centromere

M P Calos. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Two ways in which viral genomes can take advantage of the chromosomal centromere to maintain themselves long term in mammalian cells. (A) Integration is a covalent interaction with the chromosomes. It is the maintenance mode of viral genomes such as retroviruses. (B) Genomes such as BPV and EBV maintain a noncovalent close association with chromosomes, mediated by a viral protein, to ensure viral maintenance and segregation. The chromosomal centromere and the spindle attachment are depicted schematically. Viral genomes are shown in bold and, for clarity, are exaggerated greatly in size in relation to the chromosome. (Illustration drawn by Julie Phillips.)
See this image and copyright information in PMC

Comment on

References

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