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. 1998 Feb;54(2):167-70.
doi: 10.1007/s000180050138.

In vitro antiviral activity on dengue virus of marine natural products

M Laille  1 , F Gerald, C Debitus
Affiliations

In vitro antiviral activity on dengue virus of marine natural products

M Laille et al. Cell Mol Life Sci. 1998 Feb.

Abstract

Metabolites isolated from marine invertebrates, callipeltin A, crambescidin, ptilomycalin A, celeromycalin, gymnochrome B, gymnochrome D and isogymnochrome D previously shown bioactive on either herpes simplex virus 1 or human immunodeficiency virus, were tested on a new in vitro bioassay using the dengue virus 1. Only gymnochrome D and isogymnochrome D isolated from the living fossil crinoid Gymnocrinus richeri are highly potent dengue antiviral agents.

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