Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1998 Jan;34(1):1-8.
doi: 10.1007/s11626-998-0040-y.

Cell cross-contamination in cell cultures: the silent and neglected danger

Affiliations
Review

Cell cross-contamination in cell cultures: the silent and neglected danger

O Markovic et al. In Vitro Cell Dev Biol Anim. 1998 Jan.

Abstract

Cell cross-contamination in cell cultures is a common problem during cell culturing and use. Contamination invalidates research results, compromises the comparison of results between laboratories, reduces reproducibility required in industrial production of cell lines, and may lead to unusable therapeutic products. The problem can be solved by increasing the awareness of its seriousness and by introducing regular quality control of cell cross-contamination in every laboratory where cells are grown and used.

PubMed Disclaimer

References

    1. Q Rev Biol. 1966 Jun;41(2):124-30 - PubMed
    1. J Exp Med. 1950 Jan 1;91(1):1-13 - PubMed
    1. Natl Cancer Inst Monogr. 1968 Dec;29:55-7 - PubMed
    1. Science. 1977 Mar 25;195(4284):1345-8 - PubMed
    1. J Immunol. 1971 Aug;107(2):613-5 - PubMed

LinkOut - more resources