Oxidative modifications in nitrosative stress
- PMID: 9546208
- DOI: 10.1038/nsb0498-247
Oxidative modifications in nitrosative stress
Abstract
The molecular basis of redox sensitivity in proteins is not well understood. Here we consider a continuum of NO- and O2-related modifications of cysteine residues that constitute biological signaling events on the one hand and hallmarks of nitrosative and oxidative stresses on the other.
Comment on
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Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers.Nat Struct Biol. 1998 Apr;5(4):267-71. doi: 10.1038/nsb0498-267. Nat Struct Biol. 1998. PMID: 9546215
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