Breaking up is easy with esters
- PMID: 9546209
- DOI: 10.1038/nsb0498-249
Breaking up is easy with esters
Abstract
Formation of an internal (thio)ester bond activates numerous in vivo protein autoprocessing pathways including pyruvoyol group synthesis, autoproteolysis, protein splicing, enzyme activation and protein targeting. Structural analysis of precursors, intermediates and products is fine tuning our understanding of the mechanisms of these reactions.
Comment on
-
Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing.Nat Struct Biol. 1998 Apr;5(4):289-93. doi: 10.1038/nsb0498-289. Nat Struct Biol. 1998. PMID: 9546220
Publication types
MeSH terms
Substances
LinkOut - more resources
Molecular Biology Databases