doi: 10.1016/0014-2999(76)90337-x.
Effects of zinc chloride on gastric secretion and ulcer formation in pylorus-occluded rats
- PMID: 954846
- DOI: 10.1016/0014-2999(76)90337-x
Item in Clipboard
Effects of zinc chloride on gastric secretion and ulcer formation in pylorus-occluded rats
Eur J Pharmacol.
1976 Aug.
Abstract
The effects of 10-day pretreatment with i.p. injections of zinc chloride, 16 mg/kg, on gastric secretion and on gastric ulceration induced by stress or by acid accumulation were examined in pylorus-occluded rats. Zinc chloride pretreatment significantly reduced the volume of gastric secretion and the total acid output as well as the incidence of gastric ulcers induced either by stress or by acid accumulation. The findings support the idea zinc compounds may be useful in the treatment of gastric ulcers.
Similar articles
-
The effects of metiamide on gastric secretion and stress ulceration in rats.Eur J Pharmacol. 1975 Sep-Oct;33(2):277-82. doi: 10.1016/0014-2999(75)90171-5. Eur J Pharmacol. 1975. PMID: 1183477
-
The effects of zinc sulphate on gastric histamine release and ulcer formation in stressed pylorus-occluded rats.Pharmacol Res Commun. 1977 Sep;9(8):679-88. doi: 10.1016/s0031-6989(77)80059-3. Pharmacol Res Commun. 1977. PMID: 73197 No abstract available.
-
Gastric ulcers induced by acid accumulation and by stress in pylorus-occluded rats.Eur J Pharmacol. 1974 Apr;26(1):15-21. doi: 10.1016/0014-2999(74)90068-5. Eur J Pharmacol. 1974. PMID: 4831982 No abstract available.
-
Zinc compounds, a new treatment in peptic ulcer.Drugs Exp Clin Res. 1989;15(2):83-9. Drugs Exp Clin Res. 1989. PMID: 2661183 Review.
-
Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16, 16-dimethyl PGE2. Intravenous, oral and intrajejunal administration.Gastroenterology. 1976 Mar;70(3):359-70. Gastroenterology. 1976. PMID: 174967 Review.
Cited by
-
Zinc deficiency delays gastric ulcer healing in rats.Dig Dis Sci. 1995 Jun;40(6):1340-4. doi: 10.1007/BF02065548. Dig Dis Sci. 1995. PMID: 7781457
-
Mechanism of acid secretory changes in rat stomach after damage by taurocholate: role of nitric oxide, histamine, and sensory neurons.Dig Dis Sci. 1997 Mar;42(3):645-53. doi: 10.1023/a:1018875932503. Dig Dis Sci. 1997. PMID: 9073152
-
Black Salve (or escharotics). A picture about an unorthodox medical preparation in oncology.Skin Health Dis. 2023 May 9;3(3):e241. doi: 10.1002/ski2.241. eCollection 2023 Jun. Skin Health Dis. 2023. PMID: 37275421 Free PMC article.
-
Effects of zinc-aspartate and zinc-glycinate in healthy rats and on reserpine-induced gastric lesions.Biol Trace Elem Res. 1988 Aug;16(3):253-67. doi: 10.1007/BF02797140. Biol Trace Elem Res. 1988. PMID: 2484553
-
Secretagogue-dependent and -independent transport of zinc hydration forms in rat parietal cells.Pflugers Arch. 2016 Nov;468(11-12):1877-1883. doi: 10.1007/s00424-016-1889-3. Epub 2016 Oct 19. Pflugers Arch. 2016. PMID: 27757581
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
