The effect of phototherapy on renal blood flow velocity in preterm infants

Abstract

Mean renal blood flow velocity (RBFV) was studied with two-dimensional/ pulsed Doppler ultrasound and relative renal vascular resistance (RVR) was calculated before, during, and after phototherapy treatment in 30 preterm infants (gestational age < or = 32 weeks) who were treated for a minimum of 12 h with phototherapy for nonhemolytic hyperbilirubinemia. RBFV decreased, whereas RVR increased significantly after the initiation of phototherapy. In 'healthy' (nonventilated) infants RBFV and RVR returned to baseline values after discontinuation of phototherapy. Whereas in 'unhealthy' (ventilated) infants, RBFV and RVR did not return to baseline values after discontinuation of phototherapy. In 16 infants (> 50% of the cases) the ductus arteriosus reopened during phototherapy.