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Case Reports
. 1998 Feb;29(3):251-7.
doi: 10.1016/s0920-1211(97)00056-9.

Comparison of EEG, MRI and PET in reading epilepsy: a case report

M J Koepp  1 , M L Hansen, R M Pressler, D J Brooks, U Brandl, B Guldin, J S Duncan, S Ried
Affiliations
Case Reports

Comparison of EEG, MRI and PET in reading epilepsy: a case report

M J Koepp et al. Epilepsy Res. 1998 Feb.

Abstract

The pathophysiological and neuroanatomical bases of reading epilepsy (RE) are unclear. We performed video-EEG, high quality MRI and [11C]diprenorphine PET in a patient with RE to detect structural and functional abnormalities. EEG showed multifocal seizure onset bilaterally in temporal and fronto-central regions. MRI was normal, whereas [11C]diprenorphine PET revealed peri-ictal opioid binding decreases in both temporal lobes and the left frontal lobe. These findings confirm that RE is due to abnormal activity in the network subserving reading.

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