The effects of strength training and disuse on the mechanisms of fatigue

Abstract

Increases in force, electromyography, reflex potentiation, muscle action potential amplitude and protein synthesis occur with strength training. Training-induced increases in the efficiency of the neuromuscular system and capacity of the muscle to generate force result in an improved ability to cope with a submaximal load. There is also some evidence of improved fatigue resistance with maximal contractions which could be attributed to a prolongation of membrane excitation or decreased antagonist activity with training. On the other hand, although a variety of factors including strength are diminished with disuse, a number of studies have demonstrated no significant difference in the rate of fatigue with maximal contractions (fatigue index) between trained, untrained and disused muscle. Equivalent control and disuse fatigue indexes in some studies might be attributed to decreased muscle activation resulting in a comparison of maximal (control) and submaximal (disuse) efforts. Furthermore, increases in the duration of muscle membrane electrical propagation with disuse may increase the quantity of Ca++ released, augmenting force production. In addition, the smaller volume of disused muscle may allow a more efficient diffusion of oxygen and energy substrates in comparison with a hypertrophied muscle.