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Review
. 1998 Apr 25;316(7140):1299-302.
doi: 10.1136/bmj.316.7140.1299.

Food allergy

C Bindslev-Jensen  1
Affiliations
Review

Food allergy

C Bindslev-Jensen. BMJ. .
No abstract available

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Figures

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Common products containing preservatives
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Patients allergic to birch pollen may have cross reactions with some foods (eg, apples, peaches)
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Cross reactivity between birch pollen and apple in patient with springtime hay fever and oral allergy syndrome after ingestion of apple
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Fresh fruit can be used for skin prick testing for fruit allergy
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Top: Effect on symptoms of introducing restricted diet (elimination of suspected offending food) then reintroducing normal diet then returning to restricted diet in a patient who was eventually confirmed as being allergic to wheat and rye in a double blind, placebo controlled food challenge. Bottom: Effect on symptoms of a very strict elimination diet in a patient with atopic dermatitis. Although symptoms decreased initially, they had returned to normal levels by week 10 (although the diet was still being maintained). If at week 8 the patient had been given an open challenge or had returned to a normal diet, a food related exacerbation would have been suspected and false conclusions drawn. Especially in diseases with a high degree of spontaneous fluctuations in severity of symptoms a double blind, placebo controlled food challenge is mandatory, and care must be taken to avoid overinterpretation of the results
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Figure
Reaction pattern during titrated double blind, placebo controlled food challenge in patient allergic to eggs. With maximum challenge (50 mg of egg), the patient reacted with a systemic reaction within two minutes of challenge. Blood pressure was maintained. The next day, exacerbation of the patient’s atopic dermatitis occurred
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