Neuroleptic malignant syndrome related to use of clozapine
- PMID: 9558834
Neuroleptic malignant syndrome related to use of clozapine
Abstract
A 19-year-old man presented to a community hospital with a sudden change in level of consciousness, fever, and muscle rigidity. The patient had a history of schizophrenia and was being treated with clozapine. Despite a high index of suspicion for neuroleptic malignant syndrome, definitive care was delayed for more than 24 hours after the patient was transferred to a tertiary care center. This case illustrates the importance of primary care physicians being able to recognize and diagnose this syndrome, particularly as the use of atypical antipsychotic agents increases.
Similar articles
-
[Neuroleptic malignant syndrome after 30 years treatment with clozapine: a rarely seen differential diagnosis on intensive care units].Anasthesiol Intensivmed Notfallmed Schmerzther. 2006 Feb;41(2):125-7. doi: 10.1055/s-2005-921089. Anasthesiol Intensivmed Notfallmed Schmerzther. 2006. PMID: 16493563 German.
-
Clozapine-induced neuroleptic malignant syndrome: clozapine monotherapy rechallenge in a case of previous NMS.Can J Psychiatry. 1996 May;41(4):258. Can J Psychiatry. 1996. PMID: 8726793 No abstract available.
-
Atypical neuroleptic malignant syndrome with long-term clozapine.Crit Care Resusc. 2007 Dec;9(4):338-40. Crit Care Resusc. 2007. PMID: 18052897
-
[Neuroleptic malignant syndrome and atypical antipsychotics: a brief review].Encephale. 2008 Dec;34(6):618-24. doi: 10.1016/j.encep.2007.11.007. Epub 2008 Apr 2. Encephale. 2008. PMID: 19081460 Review. French.
-
Neuroleptic treatment of schizophrenia.Compr Ther. 1992 Jan;18(1):30-5. Compr Ther. 1992. PMID: 1346590 Review. No abstract available.