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Case Reports
. 1998 Mar;98(3):168-9.

Neuroleptic malignant syndrome related to use of clozapine

Affiliations
  • PMID: 9558834
Case Reports

Neuroleptic malignant syndrome related to use of clozapine

J S Trayer et al. J Am Osteopath Assoc. 1998 Mar.

Abstract

A 19-year-old man presented to a community hospital with a sudden change in level of consciousness, fever, and muscle rigidity. The patient had a history of schizophrenia and was being treated with clozapine. Despite a high index of suspicion for neuroleptic malignant syndrome, definitive care was delayed for more than 24 hours after the patient was transferred to a tertiary care center. This case illustrates the importance of primary care physicians being able to recognize and diagnose this syndrome, particularly as the use of atypical antipsychotic agents increases.

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