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. 1976 Aug;127(2):832-6.
doi: 10.1128/jb.127.2.832-836.1976.

Characterization of an Acholeplasma laidlawii variant with a REP- phenotype

J A Nowak, J Das, J Maniloff

Characterization of an Acholeplasma laidlawii variant with a REP- phenotype

J A Nowak et al. J Bacteriol. 1976 Aug.

Abstract

An Acholeplasma laidlawii variant has been isolated that has a REP- phenotype. The properties of this variant, relative to parental cells, are: (i) it exhibits no change in cell growth kinetics; (ii) it does not propagate single-stranded deoxyribonucleic acid (DNA) mycoplasmaviruses but does propagate double-stranded DNA mycoplasmaviruses; (iii) it converts parental circular single-stranded mycoplasmavirus DNA to double-stranded replicative forms that are not replicated further; (iv) it exhibits no change in host modification and restriction; and (v) it has an increased ultraviolet light sensitivity. The REP- isolate is the first stable mycoplasma variant to which a physiological defect has been attributed.

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References

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    1. Biochem Biophys Res Commun. 1975 Sep 16;66(2):599-605 - PubMed
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