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Case Reports
. 1998 Mar 5;155(2):178-81.
doi: 10.1016/s0022-510x(97)00304-3.

Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis

Affiliations
Case Reports

Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis

C Eggers et al. J Neurol Sci. .

Abstract

A patient had a paraneoplastic autonomic, then sensory, then sensory-motor neuropathy with small cell lung carcinoma and a high titer Anti-Hu antibody to nuclei of neuronal cells. As an unusual finding there was electrophysiological and pathological evidence of demyelination and a peripheral nerve microvasculitis. The relationship of microvasculitis and peripheral nerve demyelination is discussed and their occurrence with paraneoplastic anti-Hu-associated sensory neuropathy is suggested not to be by chance.

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