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Case Reports
. 1998 Mar 15;93(3):170-3.
doi: 10.1007/BF03044834.

[Coccidioidomycosis as the cause of granulomatous hepatitis]

[Article in German]
B Zangerl  1 , G Edel, J von Manitius, H A Schmidt-Wilcke
Affiliations
Case Reports

[Coccidioidomycosis as the cause of granulomatous hepatitis]

[Article in German]
B Zangerl et al. Med Klin (Munich). .

Abstract

The case of 36-year-old man is reported who fell ill with a febrile infection, shortly after returning from several weeks to Mexico.

Examination: Chest X-ray revealed a pulmonary infiltration. Also, the levels of liver function tests (gamma-GT, alkaline phosphatase, SGOT, SGPT) were clearly increased. As there were no signs of extended bile ducts in ultrasonics, a liver biopsy was indicated. The histology showed a granulomatous hepatitis.

Diagnosis: The exposure during the Mexico-trip, the pulmonary infiltration, the histology and the significant raised titers in specific serological tests led to the diagnosis of a general infection by the fungus coccidioides immitis. In addition to pathogenetic aspects of coccidioidomycosis the diagnostic approaches and relevant therapeutic strategies are discussed.

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