Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1998 Apr;11(2):231-66.
doi: 10.1128/CMR.11.2.231.

Natural pathogens of laboratory mice, rats, and rabbits and their effects on research

D G Baker  1
Affiliations
Review

Natural pathogens of laboratory mice, rats, and rabbits and their effects on research

D G Baker. Clin Microbiol Rev. 1998 Apr.

Abstract

Laboratory mice, rats, and rabbits may harbor a variety of viral, bacterial, parasitic, and fungal agents. Frequently, these organisms cause no overt signs of disease. However, many of the natural pathogens of these laboratory animals may alter host physiology, rendering the host unsuitable for many experimental uses. While the number and prevalence of these pathogens have declined considerably, many still turn up in laboratory animals and represent unwanted variables in research. Investigators using mice, rats, and rabbits in biomedical experimentation should be aware of the profound effects that many of these agents can have on research.

PubMed Disclaimer

References

    1. Abdel-Ghaffar F, Marzouk M, Ashour M B, Mosaad M N. Effects of Eimeria labbeana and E. stiedai infection on the activity of some enzymes in the serum and liver of their hosts. Parasitol Res. 1990;76:440–443. - PubMed
    1. Abzug M J. Identification of trophoblastic giant cells as the initial principal target of early gestational murine enterovirus infection. Placenta. 1993;14:137–148. - PubMed
    1. Acha-Orbea H, MacDonald H R. Superantigens of mouse mammary tumor virus. Annu Rev Immunol. 1995;13:459–486. - PubMed
    1. Alexander L K, Keene B W, Baric R S. Echocardiographic changes following rabbit coronavirus infection. Adv Exp Med Biol. 1995;380P:113–115. - PubMed
    1. Aliouat E M, Dei-Cas E, Ouaissi A, Palluault F, Soulez B, Camus D. In vitro attachment of Pneumocystis carinii from mouse and rat origin. Biol Cell. 1993;77:209–217. - PubMed

MeSH terms