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. 1976;38(3-4):173-80.
doi: 10.1007/BF01249437.

Distribution of dopamine in the rat cerebral cortex

W Kehr, M Lindqvist, A Carlsson

Distribution of dopamine in the rat cerebral cortex

W Kehr et al. J Neural Transm. 1976.

Abstract

The rat cerebral neocortex was sectioned by 3 transverse cuts and analyzed for dopamine and noradrenaline. Dopamine concentration decreased gradually from the rostral (97 +/- 4 ng/g) to the caudal (59 +/- 2 ng/g) end of the neocortex. Also, the noradrenaline concentration was highest in the rostral part (269 +/- 6 ng/g) and decreased gradually reaching a concentration of 238 +/- 3 ng/g in the caudal part. Since the quotient dopamine/noradrenaline showed similar changes in the neocortex parts investigated the data support the view that dopamine serves as a transmitter in cortical neurons apart from being a precursor for noradrenaline.

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References

    1. Br J Pharmacol. 1973 Aug;48(4):699-714 - PubMed
    1. J Neural Transm. 1974;35(4):307-17 - PubMed
    1. Naunyn Schmiedebergs Arch Pharmacol. 1972;275(2):153-68 - PubMed
    1. Science. 1973 Nov 2;182(4111):499-501 - PubMed
    1. Brain Res. 1974 Mar 8;67(3):439-56 - PubMed

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