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Review
. 1998 Feb;8(1):149-56.
doi: 10.1016/s0959-4388(98)80018-4.

Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy

G W Davis  1 , C S Goodman
Affiliations
Review

Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy

G W Davis et al. Curr Opin Neurobiol. 1998 Feb.

Abstract

When experimentally challenged with perturbations in synaptic structure and function, neurons have the remarkable ability to regulate their synaptic efficacy back to the normal range. Recent genetic analysis has provided insights into the mechanisms controlling this form of synaptic homeostasis, with implications for our understanding of synaptic development and plasticity.

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