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Comparative Study
. 1998 Apr;21(4):525-9.
doi: 10.2337/diacare.21.4.525.

Childhood diabetes in China. Enormous variation by place and ethnic group

Z Yang  1 , K Wang, T Li, W Sun, Y Li, Y F Chang, J S Dorman, R E LaPorte
Affiliations
Comparative Study

Childhood diabetes in China. Enormous variation by place and ethnic group

Z Yang et al. Diabetes Care. 1998 Apr.

Abstract

Objective: To investigate the incidence rate of IDDM in China.

Research design and methods: The Chinese IDDM registry was established in 1991 as part of the World Health Organization's Multinational Project for Childhood Diabetes (DiaMond) project. Twenty-two centers were developed to monitor the incidence of IDDM in children < 15 years of age. The population under investigation includes > 20 million individuals, representing approximately 7% of the children in China. Capture-recapture methods were used to estimate the ascertainment.

Results: The overall ascertainment-corrected IDDM incidence rate in China was 0.51 per 100,000, the lowest rate ever reported. There was a 12-fold geographic variation (0.13-1.61 per 100,000). In general, the incidence rate was higher in the north and the east. There was a sixfold difference among ethnic groups (highest: Mongol group, 1.82 per 100,000; lowest: Zhuang group, 0.32 per 100,000).

Conclusions: China has an extremely low overall IDDM incidence rate. China also has the greatest geographic and ethnic variation seen for any country.

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