Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1998 May 9;316(7142):1434-7.
doi: 10.1136/bmj.316.7142.1434.

Secondary prevention clinics for coronary heart disease: randomised trial of effect on health

Affiliations
Clinical Trial

Secondary prevention clinics for coronary heart disease: randomised trial of effect on health

N C Campbell et al. BMJ. .

Abstract

Objective: To evaluate the effects of secondary prevention clinics run by nurses in general practice on the health of patients with coronary heart disease.

Design: Randomised controlled trial of clinics over one year with assessment by self completed postal questionnaires and audit of medical records at the start and end of the trial.

Setting: Random sample of 19 general practices in northeast Scotland.

Subjects: 1173 patients (685 men and 488 women) under 80 years with working diagnoses of coronary heart disease who did not have terminal illness or dementia and were not housebound.

Intervention: Clinic staff promoted medical and lifestyle aspects of secondary prevention and offered regular follow up.

Main outcome measures: Health status measured by the SF-36 questionnaire, chest pain by the angina type specification, and anxiety and depression by the hospital anxiety and depression scale. Use of health services before and during the study.

Results: There were significant improvements in six of eight health status domains (all functioning scales, pain, and general health) among patients attending the clinic. Role limitations attributed to physical problems improved most (adjusted difference 8.52, 95% confidence interval 4.16 to 12. 9). Fewer patients reported worsening chest pain (odds ratio 0.59, 95% confidence interval 0.37 to 0.94). There were no significant effects on anxiety or depression. Fewer intervention group patients required hospital admissions (0.64, 0.48 to 0.86), but general practitioner consultation rates did not alter.

Conclusions: Within their first year secondary prevention clinics improved patients' health and reduced hospital admissions.

PubMed Disclaimer

Figures

Figure
Figure
Randomisation and exclusion of patients in trial

Comment in

References

    1. Moher M, Schofield T, Weston S, Fullard E. Managing established coronary heart disease. BMJ. 1997;314:69–70. - PMC - PubMed
    1. Antiplatelet Trialists’ Collaboration. Collaborative overview of randomised trials of antiplatelet therapy. 1. Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ. 1994;308:81–106. - PMC - PubMed
    1. Browner WS, Hulley SB. Clinical trials of hypertension treatment: implications for subgroups. Hypertension. 1989;13(suppl 1):151–156. - PubMed
    1. Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian simvastatin survival study (4S) Lancet. 1994;344:1383–1389. - PubMed
    1. Sacks FM, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med. 1996;335:1001–1009. - PubMed

Publication types

MeSH terms