Viral infections of the oral mucosa in children: a clinical review

Abstract

The oral cavity is a microcosm of the world around us, exposed to a variety of microorganisms present in the local environment. Some of these microorganisms establish a permanent presence in the oral tissues, which serve as a suitable growth medium. These locations include soft and hard tissue, areas of high and low oxygen content, flowing secretions and dryness, and flat or grooved surfaces. Most of the normal oral flora does not cause disease; some even provide a protective benefit. However, occasionally one or more groups become pathologic, producing a disease that may have serious consequences for the host. Many of the pathologic microorganisms are viruses, and children are particularly prone to such infections, since their immune systems are still in the development stage. The learning objective of this article is to review the viral infections of the oral mucosa in children, including varicella, herpes zoster, mononucleosis, and herpangina.