[The efficacy of lithium carbonate and Contemnol in preventing affective and schizoaffective psychoses]

Abstract

Two groups of patients (30 patients in each group) were treated by lithium carbonate and contemnol. High preventive efficiency of both drugs was found: average annual duration of manic and depressive exacerbation as well as their frequency decreased practically by equal value--40-50%. The efficiency was somewhat higher in the group of patients treated by contemnol (80%) as compared with the group on lithium carbonate (70%). Total number of side-effects and spontaneous complaints was twice as much in prophylaxis by lithium carbonate. Wide application of contemnol in psychiatric practice for prophylaxis of aggravations (fits) of affective and schizoaffective psychoses is recommended.