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Review
. 1998 Feb;77(2):135-48.
doi: 10.1016/s0163-7258(97)00111-3.

Molecular markers of carcinogenesis

P W Brandt-Rauf  1 , M R Pincus
Affiliations
Free article
Review

Molecular markers of carcinogenesis

P W Brandt-Rauf et al. Pharmacol Ther. 1998 Feb.
Free article

Abstract

The protein products of oncogenes and tumor suppressor genes play critical roles in the development of many cancers. The expression of a number of these proteins can be detected in extracellular fluids such as blood. This article reviews the literature on the application of methods for the detection of the proteins of oncogenes and tumor suppressor genes in the blood of humans with cancer or at risk for the development of cancer. The detection of these proteins in blood may be useful molecular markers of carcinogenesis that could play an important part in cancer diagnosis, prognosis, and prevention.

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