Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1998 Mar:41 Suppl B:93-7.
doi: 10.1093/jac/41.suppl_2.93.

Roxithromycin treatment for diarrhoea caused by Cryptosporidium spp. in patients with AIDS

D E Uip  1 , A L Lima, V S Amato, M Boulos, V A Neto, D Bem David
Affiliations
Clinical Trial

Roxithromycin treatment for diarrhoea caused by Cryptosporidium spp. in patients with AIDS

D E Uip et al. J Antimicrob Chemother. 1998 Mar.

Abstract

In view of the action of newer macrolide antibiotics on intracellular protozoa, we have investigated the efficacy of roxithromycin in the treatment of cryptosporidiosis in 26 patients with AIDS. Cryptosporidiosis was confirmed either by faecal examination for parasites (modified Kinyoun method) or by detection of the parasite in biopsy material obtained by colonoscopy. Patients received oral roxithromycin (300 mg bd) for 4 weeks. Twenty-two patients completed the study. At the end of the study, 15 patients (68%) were considered to be cured and six patients (27%) improved, and treatment failed in one patient (5%). We conclude that roxithromycin is a useful treatment for diarrhoea caused by Cryptosporidium spp. associated with AIDS.

PubMed Disclaimer

Publication types