The safety of pyrimethamine and sulfadoxine for the prevention of Pneumocystis carinii pneumonia
- PMID: 9580544
- DOI: 10.3109/00365549709035901
The safety of pyrimethamine and sulfadoxine for the prevention of Pneumocystis carinii pneumonia
Abstract
The medical records of 157 patients taking pyrimethamine-sulfadoxine for Pneumocystis carinii pneumonia prophylaxis were reviewed for assessment of safety and tolerance. 11 patients had experienced side effects, 7 (1 each: neutropenia, Stevens-Johnson, hepatic abnormalities; 2 each: subjective and hypersensitivity reactions) leading to a discontinuation of the drugs.
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