Review
doi: 10.1016/s0968-0004(98)01192-x.
Iron and copper transport in yeast and its relevance to human disease
Affiliations
- PMID: 9584616
- DOI: 10.1016/s0968-0004(98)01192-x
Item in Clipboard
Review
Iron and copper transport in yeast and its relevance to human disease
Trends Biochem Sci.
1998 Apr.
Abstract
Recent progress in the field of copper and iron metabolism has resulted from a convergence of human and yeast genetics. The mechanisms of iron and copper transport are remarkably conserved between yeast and humans. Studies of the yeast homologs of human disease genes involved in metal homeostasis have shed light on the pathophysiology of these disorders.
Similar articles
-
Yeast, a model organism for iron and copper metabolism studies.Biometals. 2003 Mar;16(1):185-97. doi: 10.1023/a:1020771000746. Biometals. 2003. PMID: 12572678 Review.
-
A genetic approach to elucidating eukaryotic iron metabolism.FEBS Lett. 1994 Nov 28;355(2):109-13. doi: 10.1016/0014-5793(94)01111-7. FEBS Lett. 1994. PMID: 7982480 Review.
-
Genetic disorders affecting proteins of iron and copper metabolism: clinical implications.Intern Med. 2002 Oct;41(10):762-9. doi: 10.2169/internalmedicine.41.762. Intern Med. 2002. PMID: 12412992 Review.
-
Saccharomyces cerevisiae mutants altered in vacuole function are defective in copper detoxification and iron-responsive gene transcription.Yeast. 1997 Dec;13(15):1423-35. doi: 10.1002/(SICI)1097-0061(199712)13:15<1423::AID-YEA190>3.0.CO;2-C. Yeast. 1997. PMID: 9434348
-
Genetic determinants of trace element metabolism.Ann Clin Lab Sci. 1999 Jan-Mar;29(1):24-32. Ann Clin Lab Sci. 1999. PMID: 10074965 Review. No abstract available.
Cited by
-
Cloning and characterization of a maize cytochrome-b5 reductase with Fe3+-chelate reduction capability.Biochem J. 1999 Mar 1;338 ( Pt 2)(Pt 2):499-505. Biochem J. 1999. PMID: 10024528 Free PMC article.
-
Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells.Biochem J. 2001 May 15;356(Pt 1):61-9. doi: 10.1042/0264-6021:3560061. Biochem J. 2001. PMID: 11336636 Free PMC article.
-
Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels.Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13641-5. doi: 10.1073/pnas.95.23.13641. Proc Natl Acad Sci U S A. 1998. PMID: 9811853 Free PMC article.
-
The RNA world and the origin of metabolic enzymes.Biochem Soc Trans. 2014 Aug;42(4):985-8. doi: 10.1042/BST20140132. Biochem Soc Trans. 2014. PMID: 25109990 Free PMC article. Review.
-
Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy.Inorganics (Basel). 2018;6(4):126. doi: 10.3390/inorganics6040126. Epub 2018 Nov 30. Inorganics (Basel). 2018. PMID: 33912613 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases
