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Review
. 1998:16:163-200.
doi: 10.1146/annurev.immunol.16.1.163.

Transcriptional regulation during B cell development

A Henderson  1 , K Calame
Affiliations
Review

Transcriptional regulation during B cell development

A Henderson et al. Annu Rev Immunol. 1998.

Abstract

Information is increasingly available concerning the molecular events that occur during primary and antigen-dependent stages of B cell development. In this review the roles of transcription factors and coactivators are discussed with respect to changes in expression patterns of various genes during B cell development. Transcriptional regulation is also discussed in the context of developmentally regulated immunoglobulin gene V(D)J recombination, somatic hypermutation, and isotype switch recombination.

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