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. 1998 May;61(5):706-8.
doi: 10.1021/np9800203.

Antioxidant flavonoid glycosides from Daphniphyllum calycinum

E J Gamez  1 , L Luyengi, S K Lee, L F Zhu, B N Zhou, H H Fong, J M Pezzuto, A D Kinghorn
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Antioxidant flavonoid glycosides from Daphniphyllum calycinum

E J Gamez et al. J Nat Prod. 1998 May.

Abstract

A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as antioxidants in the DPPH assay.

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