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Review
. 1998 Feb;80(2):255-6.
doi: 10.1093/bja/80.2.255.

The blood-gas partition coefficient of xenon may be lower than generally accepted

T Goto  1 , K Suwa, S Uezono, F Ichinose, M Uchiyama, S Morita
Affiliations
Free article
Review

The blood-gas partition coefficient of xenon may be lower than generally accepted

T Goto et al. Br J Anaesth. 1998 Feb.
Free article

Abstract

The blood-gas partition coefficients of xenon, reported more than 25 yr ago in the literature, vary considerably from 0.13 to 0.20. Consequently, we have determined this variable by directly injecting xenon-saturated blood into a gas chromatograph-mass spectrometer. This technique yielded a blood-gas partition coefficient for xenon of 0.115 (95% confidence interval 0.107-0.123). The solubility in water measured identically was 0.096, consistent with the reported value of 0.085. These data and a detailed review of the literature strongly suggest that the blood-gas partition coefficient of xenon may be lower than the generally accepted value of 0.14.

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