Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1998 Mar;78(3):273-4.
doi: 10.1136/adc.78.3.273.

Thrombocytopenic purpura as adverse reaction to recombinant hepatitis B vaccine

F Ronchi  1 , P Cecchi, F Falcioni, A Marsciani, G Minak, G Muratori, P L Tazzari, S Beverini
Affiliations
Case Reports

Thrombocytopenic purpura as adverse reaction to recombinant hepatitis B vaccine

F Ronchi et al. Arch Dis Child. 1998 Mar.

Abstract

Three cases of immune thrombocytopenic purpura after the first dose of recombinant hepatitis B vaccine occurred in infants under 6 months of age. Other possible causes of this condition were excluded. Antiplatelet antibodies were present. A defect in platelet production was excluded in two children. Corticosteroid treatment was effective. Subsequent administration of other vaccines (against polio, diphtheria, and tetanus) did not cause relapse of thrombocytopenia.

PubMed Disclaimer

References

    1. Lancet. 1991 Nov 9;338(8776):1174-5 - PubMed
    1. Clin Infect Dis. 1992 Dec;15(6):1051 - PubMed
    1. Ann Hematol. 1995 May;70(5):267-72 - PubMed
    1. Lancet. 1994 Nov 5;344(8932):1293 - PubMed
    1. Lancet. 1994 Nov 5;344(8932):1292-3 - PubMed

Publication types